Last edited by Kajijas
Sunday, July 26, 2020 | History

4 edition of Protein-nucleic acid interactions found in the catalog.

Protein-nucleic acid interactions

structural biology

  • 307 Want to read
  • 16 Currently reading

Published by RSC Pub. in Cambridge .
Written in English

    Subjects:
  • DNA-protein interactions.,
  • RNA-protein interactions.

  • Edition Notes

    Includes bibliographical references and index.

    Statementedited by Phoebe A. Rice and Carl C. Correll.
    SeriesRSC biomolecular sciences
    ContributionsRice, Phoebe A., Correll, Carl C.
    Classifications
    LC ClassificationsQP624.75.P74 P76 2008
    The Physical Object
    Paginationxvii, 397 p. :
    Number of Pages397
    ID Numbers
    Open LibraryOL17038890M
    ISBN 100854042725
    ISBN 109780854042722
    LC Control Number2008428226

      [79] Cruceanu M, Gorelick RJ, Musier-Forsyth K, Rouzina I, Williams MC, Rapid kinetics of protein-nucleic acid interaction is a major component of HIV-1 nucleocapsid protein’s nucleic acid chaperone function, J. Mol. Biol (5) () – [Google Scholar]. Title: Interfacial Inhibitors of Protein-Nucleic Acid Interactions VOLUME: 5 ISSUE: 4 Author(s):Y. Pommier and C. Marchand Affiliation:Bldg. 37, Rm. , NIH.

    Protein-protein and protein-nucleic acid interactions including large assemblies responsible for DNA or RNA transactions and mechanisms of allostery. Multi-protein complexes and molecular machines. Structure Function studies of molecules involved in cell-cell interactions including adhesion, migration, signal transduction and mechanotransduction.   Protein–nucleic acid recognition can be understood by atomic interactions between amino acids and nucleotides (Rhodes and Stephen, ; Lavery, ; Coulocheri et al., ; Hégarat et al., ). These complexes have been analysed by several authors, for more than 30 .

    From the book: Protein-Nucleic Acid Interactions: Structural Biology Preface. Phoebe A. Rice and Carl C. Correll No abstract available This content is free to download. Please choose one of the options below to gain access. Log in Using your FREE.   Specific protein – nucleic acid (NA) interactions play a vital role in most processes in all living organisms. Such important cellular processes, as replication, transcription, translation, repair and transport of nucleic acids from the nucleus to the cytoplasm, involve specific protein – nucleic acid .


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Protein-nucleic acid interactions Download PDF EPUB FB2

Book Descriptions: The structural biology of protein-nucleic acid interactions is in some ways a mature field and in others in its infancy. High-resolution structures of protein-DNA complexes have been studied since the mid s and a vast array of such structures has now been determined, but surprising and novel structures still appear quite frequently.

The monograph approaches the study of protein-nucleic acid interactions in two distinctive ways. First, DNA-protein and RNA-protein interactions are presented together. Second, the first half of the book develops the principles of protein-nucleic acid recognition, whereas the second half applies these to more specialized : $ About this book.

The structural biology of protein-nucleic acid interactions is in some ways a mature field and in others in its infancy. High-resolution structures of protein-DNA complexes have been studied since the mid s and a vast array of such structures has now been determined, but surprising and novel structures still appear quite frequently.

The structural biology of protein-nucleic acid interactions is in some ways a mature field and in others in its infancy. High-resolution structures of protein-DNA complexes have been studied since the mid s and a vast Protein-nucleic acid interactions book of such structures has now been determined, but surprising and novel structures still appear Protein-nucleic acid interactions book : Stephen Neidle.

Protein-Nucleic Acids Interactions COVID Update: We are currently shipping orders daily. However, due to transit disruptions in some geographies, deliveries may be delayed. from book The Principles of Nucleic Acid Structure (pp) Protein—Nucleic Acid Interactions.

Chapter January This book is organized into nine part encompassing 31 chapters. The opening parts describe the principles of DNA replication and the unique chromatin structure.

These parts also examine the physical chemistry of the interactions of melting proteins with nucleic acids. Our protein-nucleic acid interactions team has rich experience in the field, and can provide various advanced and reliable analysis services against the protein or nucleic acid of interest in vivo or in vitro.

Services we are offering include but not limited to: DNA-Protein Interactions. Electrophoretic Mobility Shift Assay (EMSA). As an expert in the field of studying protein-nucleic acid interactions, Profacgen provides a powerful technique, RNA-binding proteins immunoprecipitation microarray or next generation sequencing analysis (RIP-ChIP/Seq), which has been widely used for isolating and identifying mRNA and noncoding RNAs associated with RNA-binding proteins (RBPs) in vivo.

Protein–nucleic acid interactions are sensitive to the concentrations and nature of electrolyte ions in solution (Leirmo, Harrison, Cayley, Burgess, & Record, ).We evaluated the influence of ion composition on beacon binding to preformed Cas9/sgRNA(+ 89) complex and on the Cas9/sgRNA(+ 89) assembly in assay mixtures containing mM of either NaCl, KCl, or KGlu.

The structural biology of protein-nucleic acid interactions is in some ways a mature field and in others in its infancy.

High-resolution structures of. Our Stores Are Open Book Annex Membership Educators Gift Cards Stores & Events HelpPages: Yun-Xing Wang is a structural biologist who pioneered the combined use of NMR spectroscopy, small angle X-ray scattering (SAXS), diffraction and other biophysical methods to study RNA structural biology.

His laboratory research places emphases on solving long-standing important structural biology questions and uses the gained knowledge to develop diagnostic and therapeutic. Molecular machines that act on nucleic acids, DNA and RNA are at the heart of the field of cellular information processing.

A coherent description of the interactions involved in their assembly, activities and regulation affords a quantitative understanding of how transcription factors and DNA repair proteins find their unique targets among millions of nonspecific sequences and undamaged DNA.

Analysis of protein-nucleic acid interactions with MST Interactions of proteins and nucleic acids are reported to play a pivotal role in epigenetic networks, especially in the chromatin decondensation processes (Schubert et al., ). Microscale thermophoresis (MST) is a new method that enables the quantitative analysis of molecular interactions in solution at the microliter scale.

The technique is based on the thermophoresis of. Interactions between nucleic acids and proteins are driving gene expression programs and regulating the development of organisms. The binding affinities of transcription factors to their target sites. Chemical aspects of nucleic acids come to the fore in the last third of the book, with description of interactions of small molecules with nucleic acids, protein-nucleic acid interactions and techniques used to analyse nucleic acids.

In summary, this book provides an excellent overview of the chemistry and biology of nucleic acids, at a level Reviews: 6. Overview of Protein:Nucleic Acid Interactions To order, call or Outside the United States, contact your local branch office or distributor.

In addition, the affinity and specificity of a particular protein–nucleic acid interaction can be increased through protein oligomerization or multi-protein complex formation (e.g., GCN4, glucocorticoid receptor, transcription initiation complexes, mRNA splicing complexes, RISC, etc.).

Biolayer interferometry (BLI) is a simple, optical dip‐and‐read system useful for measuring interactions between proteins, peptides, nucleic acids, small molecules, and/or lipids in real time. In BLI, a biomolecular bait is immobilized on a matrix at the tip of a fiber‐optic sensor.

Protein-Nucleic Acid Interactions › We offer a selection of easy-to-use kits for chromatin immunoprecipitation assays (ChIP), electrophoretic mobility shift assays (EMSA), and DNA pull-down assays. These kits allow you to determine which proteins interact with DNA or RNA, and analyze what proteins are present in these protein-nucleic acid.We first describe key features and determinants of bimolecular association kinetics.

Then we present an overview of theoretical and computational approaches to calculating kinetic properties. Finally, we discuss recent computational advances with selected examples of protein-nucleic acid. The thermodynamic data available in ProTherm and ProNIT are widely used by researchers to study the underlying mechanisms of protein stability upon mutations and protein–nucleic acid interactions (see the reference sections on both the websites).

This paper describes the major updates and enhancements to these databases for the last few years.